Journal
NATURE METHODS
Volume 14, Issue 3, Pages 259-+Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/NMETH.4153
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Funding
- German Federal Ministry of Education and Research (BMBF) [031L0008A]
- Alexander von Humboldt Foundation
- federal funds from the American Recovery and Reinvestment Act (ARRA) funds through the NIH, from the National Human Genome Research Institute [RC2HG005805]
- National Institute of General Medical Sciences/Center for Systems Biology [R01GM087221, S10RR027584, 2P50 GM076547]
- European Research Council [ERC-2008-AdG 233226, ERC-2014-AdG 670821]
- Swiss National Science Foundation [31003A-130530]
- Swiss National Science Foundation (SNF) [31003A_130530] Funding Source: Swiss National Science Foundation (SNF)
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We describe ProteomeTools, a project building molecular and digital tools from the human proteome to facilitate biomedical research. Here we report the generation and multimodal liquid chromatography-tandem mass spectrometry analysis of > 330,000 synthetic tryptic peptides representing essentially all canonical human gene products, and we exemplify the utility of these data in several applications. The resource (available at http://www. proteometools. org) will be extended to > 1 million peptides, and all data will be shared with the community via ProteomicsDBDB and ProteomeXchange.
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