4.8 Article

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence

Related references

Note: Only part of the references are listed.
Review Genetics & Heredity

The role of cGAS in innate immunity and beyond

Andrea Ablasser et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2016)

Article Multidisciplinary Sciences

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

Darren J. Baker et al.

NATURE (2016)

Article Multidisciplinary Sciences

Senescent intimal foam cells are deleterious at all stages of atherosclerosis

Bennett G. Childs et al.

SCIENCE (2016)

Article Multidisciplinary Sciences

Tissue damage and senescence provide critical signals for cellular reprogramming in vivo

Lluc Mosteiro et al.

SCIENCE (2016)

Review Biochemistry & Molecular Biology

Cellular senescence in aging and age-related disease: from mechanisms to therapy

Bennett G. Childs et al.

NATURE MEDICINE (2015)

Article Multidisciplinary Sciences

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases

Daxing Gao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Viruses transfer the antiviral second messenger cGAMP between cells

A. Bridgeman et al.

SCIENCE (2015)

Review Immunology

STING: infection, inflammation and cancer

Glen N. Barber

NATURE REVIEWS IMMUNOLOGY (2015)

Review Immunology

Aicardi-Goutieres syndrome and the type I interferonopathies

Yanick J. Crow et al.

NATURE REVIEWS IMMUNOLOGY (2015)

Article Immunology

TREX1 Deficiency Triggers Cell-Autonomous Immunity in a cGAS-Dependent Manner

Andrea Ablasser et al.

JOURNAL OF IMMUNOLOGY (2014)

Review Multidisciplinary Sciences

The role of senescent cells in ageing

Jan M. van Deursen

NATURE (2014)

Review Cell Biology

Cellular senescence: from physiology to pathology

Daniel Munoz-Espin et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Review Physiology

Aging, Cellular Senescence, and Cancer

Judith Campisi

ANNUAL REVIEW OF PHYSIOLOGY, VOL 75 (2013)

Review Biochemistry & Molecular Biology

The Hallmarks of Aging

Carlos Lopez-Otin et al.

Article Cell Biology

Lysosome-mediated processing of chromatin in senescence

Andre Ivanov et al.

JOURNAL OF CELL BIOLOGY (2013)

Review Medicine, Research & Experimental

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

Tamara Tchkonia et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Multidisciplinary Sciences

T-helper-1-cell cytokines drive cancer into senescence

Heidi Braumueller et al.

NATURE (2013)

Article Multidisciplinary Sciences

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Andrea Ablasser et al.

NATURE (2013)

Article Cell Biology

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

Juan Carlos Acosta et al.

NATURE CELL BIOLOGY (2013)

Article Cell Biology

Lamin B1 loss is a senescence-associated biomarker

Adam Freund et al.

MOLECULAR BIOLOGY OF THE CELL (2012)

Article Multidisciplinary Sciences

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

Tae-Won Kang et al.

NATURE (2011)

Review Pathology

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

Jean -Philippe Coppe et al.

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)

Review Biochemistry & Molecular Biology

Pattern Recognition Receptors and Inflammation

Osamu Takeuchi et al.

Review Cell Biology

The essence of senescence

Thomas Kuilman et al.

GENES & DEVELOPMENT (2010)

Article Biochemistry & Molecular Biology

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

Thomas Kuilman et al.

Article Biochemistry & Molecular Biology

Chemokine signaling via the CXCR2 receptor reinforces senescence

Juan C. Acosta et al.

Article Biochemistry & Molecular Biology

Senescence of activated stellate cells limits liver fibrosis

Valery Krizhanovsky et al.

Review Biochemistry & Molecular Biology

Cellular senescence in cancer and aging

Manuel Collado et al.

Article Cell Biology

DNA damage signaling and p53-dependent senescence after prolonged β-interferon stimulation

O Moiseeva et al.

MOLECULAR BIOLOGY OF THE CELL (2006)

Review Biochemistry & Molecular Biology

E2F target genes: unraveling the biology

AP Bracken et al.

TRENDS IN BIOCHEMICAL SCIENCES (2004)

Article Cell Biology

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

S Parrinello et al.

NATURE CELL BIOLOGY (2003)