Journal
NATURE CELL BIOLOGY
Volume 19, Issue 6, Pages 581-588Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ncb3524
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Funding
- EMBO [ALTF 534-2016]
- Institute of Science and Technology Austria [I_CAHE_IFELL01]
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The seminal observation that mechanical signals can elicit changes in biochemical signalling within cells, a process commonly termed mechanosensation and mechanotransduction, has revolutionized our understanding of the role of cell mechanics in various fundamental biological processes, such as cell motility, adhesion, proliferation and differentiation. In this Review, we will discuss how the interplay and feedback between mechanical and biochemical signals control tissue morphogenesis and cell fate specification in embryonic development.
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