Journal
NATURE CELL BIOLOGY
Volume 19, Issue 8, Pages 885-886Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ncb3585
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Funding
- NHLBI NIH HHS [R01 HL130129] Funding Source: Medline
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The lung undergoes a striking repair process in response to severe injuries such as influenza infection. A study now demonstrates that associated stem/progenitor cells are heterogeneous in nature and comprise subpopulations dominated by hypoxia/Notch or Wnt signalling. Modulation of this heterogeneity in favour of functional repair may have therapeutic value.
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