Journal
NATURE BIOTECHNOLOGY
Volume 35, Issue 4, Pages 347-+Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nbt.3804
Keywords
-
Categories
Funding
- NIH [P30-CA008748, U01-HG007033, U01-HG007893]
- Geoffrey Beene Cancer Research Foundation
- Uniting Against Lung Cancer Foundation
- Cycle for Survival Foundation
- Pershing Square Sohn Cancer Research Alliance
- Lung Cancer Research Foundation
Ask authors/readers for more resources
We present GuideScan software for the design of CRISPR guide RNA libraries that can be used to edit coding and noncoding genomic regions. GuideScan produces high-density sets of guide RNAs (gRNAs) for single- and paired-gRNA genome-wide screens. We also show that the trie data structure of GuideScan enables the design of gRNAs that are more specific than those designed by existing tools.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
