Journal
NATURE
Volume 542, Issue 7640, Pages 177-185Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nature21363
Keywords
-
Categories
Funding
- National Institutes of Health [DK052539, HL125753, Al116901]
- JDRF [2SRA-2016-147-Q-R]
- Union Chemique Belge
- Servier
Ask authors/readers for more resources
Proper regulation and management of energy, substrate diversity and quantity, as well as macromolecular synthesis and breakdown processes, are fundamental to cellular and organismal survival and are paramount to health. Cellular and multicellular organization are defended by the immune response, a robust and critical system through which self is distinguished from non-self, pathogenic signals are recognized and eliminated, and tissue homeostasis is safeguarded. Many layers of evolutionarily conserved interactions occur between immune response and metabolism. Proper maintenance of this delicate balance is crucial for health and has important implications for many pathological states such as obesity, diabetes, and other chronic non-communicable diseases.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available