Journal
NATURAL PRODUCT RESEARCH
Volume 32, Issue 7, Pages 821-825Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2017.1363754
Keywords
Aspergillus sp; isolation; structure elucidation; MRSA
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Funding
- Fundamental Research Funds for the Central Universities [2-9-2015-165]
- Key Laboratory of Marine Bioactive Substance and Modern Analytical Technique, SOA [MBSMAT-2016-04]
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One new diphenyl ether, diorcinol K (1), along with three known compounds, diorcinols D (2), F (3) and I (4) were isolated from the fermentation media of a marine-derived fungus Aspergillus sp. CUGB-F046 which was isolated from a sediment sample collected from the Bohai Sea, China. Their structures were elucidated by detailed spectroscopic methods. Compounds 1, 2 and 4 displayed significant antibacterial activities against Staphylococcus aureus and methicillinresistant S. aureus with MIC values of 3.125, 6.25 and 6.25 mu g/mL, respectively. [GRAPHICS] .
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