Journal
NATURAL PRODUCT RESEARCH
Volume 32, Issue 14, Pages 1653-1659Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2017.1395430
Keywords
Rhodamnia dumetorum; coruleoellagic acid; carbazole; gallic acid; antibacterial
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Funding
- Thailand Research Fund via Royal Golden Jubilee Ph.D. Program [PHD/0051/2557]
- TRF Senior Research Scholar [RTA5980002]
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A new coruleoellagic acid derivative, 3,3,4,4,5-pentamethylcoruleoellagic acid (1) together with nine known compounds, hexamethylcoruleoellagic acid (2), 3,4,3-tri-O-methylellagic acid (3), heptaphylline (4), 7-methoxymukonal (5), dentatin (6), sinapaldehyde (7), gallic acid (8), 2,6-dimethoxy-4H-pyran-4-one (9) and -sitosterol (10) were isolated from the stems of Rhodamnia dumetorum. Their structures were identified by physical and spectroscopic data (IR, 1D and 2D NMR, and MS). Compounds 1, 2 and 7-10 were tested for antibacterial activity against six pathogenic bacterial strains (Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica serovar Typhimurium, Staphylococcus aureus, and Methicillin resistant S. aureus (MRSA)). [GRAPHICS] .
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