4.4 Article

Two new Anti-TMV active chalconoid analogues from the root of Phyllanthus emblica

Journal

NATURAL PRODUCT RESEARCH
Volume 31, Issue 18, Pages 2143-2148

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2017.1280487

Keywords

Phyllanthus emblica; anti-TMV; emblirol A; emblirol B

Funding

  1. Natural Science Foundation of China [31260085]

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Two new chalconoid analogues, emblirol A (1) and B (2), along with three known ones (3-5), were isolated from the root of the Phyllanthus emblica L. Their structures were elucidated on the basis of spectral data. Compound 1 and 2 showed moderate anti-TMV activity with inhibition rates 79.6 and 62.1% at a concentration of 1mg/mL, respectively.

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