Journal
NATURAL PRODUCT RESEARCH
Volume 33, Issue 4, Pages 500-505Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2017.1399384
Keywords
Aralia chinensis; triterpene saponins; cardiomyocyte oxidative injury; DPPH radical scavenging activity
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Funding
- technologic large platform for comprehensive research and development of new drugs in the Twelfth Five-Year Significant New Drugs Created Science and Technology Major Projects [2012ZX09301-002-001-026]
- National Science and Technology Support Program [2012BA127B06]
- Innovation Capacity building in Anhui Science and Technology Agency [10100027-3]
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Phytochemical investigation of the stem of Aralia chinensis yielded six new oleanane-type triterpene saponins named as congmujingnosides B-G (1-6). The new ones were elucidated on the basis of the chemical and spectroscopic analysis. Protective effects of compounds 1-6 were tested against H2O2-induced H9c2 cardiomyocyte injury, and the data showed that compounds 1 and 5 had significant cell-protective effects. No significant DPPH radical scavenging activity was observed for compounds 1-6. [GRAPHICS] .
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