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CHEMICAL REVIEWS (2010)
Hydrocarbon Hydroxylation by Cytochrome P450 Enzymes
Paul R. Ortiz de Montellano
CHEMICAL REVIEWS (2010)
Structure of Cytochrome P450 PimD Suggests Epoxidation of the Polyene Macrolide Pimaricin Occurs via a Hydroperoxoferric Intermediate
Petrea M. Kells et al.
CHEMISTRY & BIOLOGY (2010)
Homology modeling, binding site identification and docking in flavone hydroxylase CYP105P2 in Streptomyces peucetius ATCC 27952
Bashistha Kumar Kanth et al.
COMPUTATIONAL BIOLOGY AND CHEMISTRY (2010)
Three-step hydroxylation of vitamin D3 by a genetically engineered CYP105A1
Keiko Hayashi et al.
FEBS JOURNAL (2010)
In vivo characterization of NcsB3 to establish the complete biosynthesis of the naphthoic acid moiety of the neocarzinostatin chromophore
Vu Thi Thu Hang et al.
FEMS MICROBIOLOGY LETTERS (2010)
Regio- and Stereospecificity of Filipin Hydroxylation Sites Revealed by Crystal Structures of Cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis
Lian-Hua Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Enhancement of recombinant enzyme activity in cpxA-deficient mutant of Escherichia coli
Ying Zhou et al.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2010)
Biooxidation of methyl group: Part 2. Evidences for the involvement of cytochromes P450 in microbial multistep oxidation of terfenadine
Amane El Ouarradi et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2010)
Natural Products Version 2.0: Connecting Genes to Molecules
Christopher T. Walsh et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Cyclization of a Cellular Dipentaenone by Streptomyces coelicolor Cytochrome P450 154A1 without Oxidation/Reduction
Qian Cheng et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Biosynthesis of 3-methoxy-5-methyl naphthoic acid and its incorporation into the antitumor antibiotic azinomycin B
Wei Ding et al.
MOLECULAR BIOSYSTEMS (2010)
Characterizing Proteins of Unknown Function: Orphan Cytochrome P450 Enzymes as a Paradigm
F. Peter Guengerich et al.
MOLECULAR INTERVENTIONS (2010)
Characterization of P450 FcpC, the Enzyme Responsible for Bioconversion of Diosgenone to Isonuatigenone in Streptomyces virginiae IBL-14
Wei Wang et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2009)
Tailoring the P450 Monooxygenase Gene for FR-008/Candicidin Biosynthesis
Shi Chen et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2009)
The pH Shift and Precursor Feeding Strategy in a Low-Toxicity FR-008/Candicidin Derivative CS103 Fermentation Bioprocess by a Mutant of Streptomyces sp FR-008
Xiangzhao Mao et al.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2009)
Cloning and Heterologous Expression of the Cyclooctatin Biosynthetic Gene Cluster Afford a Diterpene Cyclase and Two P450 Hydroxylases
Seung-Young Kim et al.
CHEMISTRY & BIOLOGY (2009)
Deciphering Biosynthesis of the RNA Polymerase Inhibitor Streptolydigin and Generation of Glycosylated Derivatives
Carlos Olano et al.
CHEMISTRY & BIOLOGY (2009)
Biosynthesis of Macrolactam BE-14106 Involves Two Distinct PKS Systems and Amino Acid Processing Enzymes for Generation of the Aminoacyl Starter Unit
Hanne Jorgensen et al.
CHEMISTRY & BIOLOGY (2009)
Crystal Structures of Cytochrome P450 105P1 from Streptomyces avermitilis: Conformational Flexibility and Histidine Ligation State
Lian-Hua Xu et al.
JOURNAL OF BACTERIOLOGY (2009)
Analysis of Transient and Catalytic Desosamine-binding Pockets in Cytochrome P-450 PikC from Streptomyces venezuelae
Shengying Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Crystal Structure of Albaflavenone Monooxygenase Containing a Moonlighting Terpene Synthase Active Site
Bin Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
One-pot fermentation of pladienolide D by Streptomyces platensis expressing a heterologous cytochrome P450 gene
Kazuhiro Machida et al.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2009)
Theoretical and Experimental Studies of the Conversion of Chromopyrrolic Acid to an Antitumor Derivative by Cytochrome P450 StaP: The Catalytic Role of Water Molecules
Yong Wang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Cleavage of Four Carbon-Carbon Bonds during Biosynthesis of the Griseorhodin A Spiroketal Pharmacophore
Zeynep Yunt et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Genomic basis for natural product biosynthetic diversity in the actinomycetes
Markus Nett et al.
NATURAL PRODUCT REPORTS (2009)
Using Sequence Similarity Networks for Visualization of Relationships Across Diverse Protein Superfamilies
Holly J. Atkinson et al.
PLOS ONE (2009)
Selective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenase
Shengying Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Sequential Asymmetric Polyketide Heterocyclization Catalyzed by a Single Cytochrome P450 Monooxygenase (AurH)
Martin E. A. Richter et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Cytochrome P450 (CYP105F2) from Streptomyces peucetius and its activity with oleandomycin
Pramod Shrestha et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2008)
Structure-Based Design of a Highly Active Vitamin D Hydroxylase from Streptomyces griseolus CYP105A1
Keiko Hayashi et al.
BIOCHEMISTRY (2008)
Crystal structure of CYP105A1 (P450SU-1) in complex with 1α,25-dihydroxyvitamin D3
Hiroshi Sugimoto et al.
BIOCHEMISTRY (2008)
Organization of the Biosynthetic Gene Cluster for the Polyketide Antitumor Macrolide, Pladienolide, in Streptomyces platensis Mer-11107
Kazuhiro Machida et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2008)
Designing a whole-cell biotransformation system in Escherichia coli using cytochrome P450 from Streptomyces peucetius
Pramod Shrestha et al.
BIOTECHNOLOGY LETTERS (2008)
Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2)
Bin Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Increase in pladienolide D production rate using a Streptomyces strain overexpressing a cytochrome P450 gene
Kazuhiro Machida et al.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2008)
Combinatorial biosynthesis of 5-O-desosaminyl erythronolide A as a potent precursor of ketolide antibiotics
Devi B. Basnet et al.
JOURNAL OF BIOTECHNOLOGY (2008)
Identification and characterization of sanH and sanI involved in the hydroxylation of pyridyl residue during nikkomycin biosynthesis in Streptomyces ansochromogenes
Zhoujie Xie et al.
CURRENT MICROBIOLOGY (2007)
Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens
Fatma Karray et al.
MICROBIOLOGY-SGM (2007)
Engineering and analysis of a self-sufficient biosynthetic cytochrome P450 PikC fused to the RhFRED reductase domain
Shengying Li et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Enzymatic total synthesis of enterocin polyketides
Qian Cheng et al.
NATURE CHEMICAL BIOLOGY (2007)
The biosynthesis of teicoplanin-type glycopeptide antibiotics:: Assignment of p450 mono-oxygenases to side chain Cyclizations of glycopeptide a47934
Bianka Hadatsch et al.
CHEMISTRY & BIOLOGY (2007)
Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2
Bin Zhao et al.
BIOCHEMISTRY (2007)
Crystal structures and catalytic mechanism of cytochrome P450 StaP that produces the indolocarbazole skeleton
Masatomo Makino et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Electron transport pathway for a Streptomyces cytochrome P450 -: Cytochrome P450 105D5-catalyzed fatty acid hydroxylation in Streptomyces coelicolor A3(2)
Young-Jin Chun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Variations on a (t)heme - novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily
Andrew W. Munro et al.
NATURAL PRODUCT REPORTS (2007)
Functional analysis of DesVIII homologues involved in glycosylation of macrolide antibiotics by interspecies complementation
Jay Sung Joong Hong et al.
GENE (2007)
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp CK4412
Si-Sun Choi et al.
MICROBIOLOGY-SGM (2007)
Mechanisms of cytochrome p450 substrate oxidation: MiniReview
F. Peter Guengerich
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2007)
Understanding electron transport systems of Streptomyces cytochrome P450
Y. -J. Chun et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2006)
The cytochrome P450 gene family CYP157 does not contain EXXR in the K-helix reducing the absolute conserved P450 residues to a single cysteine
Sanjeewa Rupasinghe et al.
FEBS LETTERS (2006)
Pentalenolactone biosynthesis.: Molecular cloning and assignment of biochemical function to PtII, a cytochrome p450 of Streptomyces avermitilis
Richard Quaderer et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Staurosporine and rebeccamycin aglycones are assembled by the oxidative action of StaP, StaC, and RebC on chromopyrrolic acid
Annaleise R. Howard-Jones et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae
David H. Sherman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Inactivation of gilGT, encoding a C-glycosyltransferase, and gilOlll, encoding a p450 enzyme, allows the details of the late biosynthetic pathway to gilvocarcin V to be delineated
Tao Liu et al.
CHEMBIOCHEM (2006)
Analysis of the loading and hydroxylation steps in lankamycin biosynthesis in Streptomyces rochei
Kenji Arakawa et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)
Neopikromycin and novapikromycin from the pikromycin biosynthetic pathway of Streptomyces venezuelae
Sang Kil Lee et al.
JOURNAL OF NATURAL PRODUCTS (2006)
Characterization of the P450 monooxygenase NysL, responsible for C-10 hydroxylation during biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei
O Volokhan et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2006)
Biosynthesis of the terpene phenalinolactone in Streptomyces sp Tu6071:: Analysis of the gene cluster and generation of derivatives
C Dürr et al.
CHEMISTRY & BIOLOGY (2006)
Hydroxylation of testosterone by bacterial cytochromes P450 using the Escherichia coli expression system
H Agematu et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2006)
Substrate Specificity of the Macrolide-Glycosylating Enzyme Pair DesVII/DesVIII: Opportunities, Limitations, and Mechanistic Hypotheses
SA Borisova et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
The complete biosynthetic gene cluster of the 28-membered polyketide macrolactones, halstoctacosanolides, from Streptomyces halstedii HC34
S Tohyama et al.
JOURNAL OF ANTIBIOTICS (2006)
Reactive nitrogen species generated by heme proteins: Mechanism of formation and targets
Raffaella Roncone et al.
COORDINATION CHEMISTRY REVIEWS (2006)
Role of active site water molecules and substrate hydroxyl groups in oxygen activation by cytochrome P450 158A2 - A new mechanism of proton transfer
B Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The plmS2-encoded cytochrome P450 monooxygenase mediates hydroxylation of phoslactomycin B in Streptomyces sp strain HK803
MS Ghatge et al.
JOURNAL OF BACTERIOLOGY (2005)
Biosynthesis of hexahydroxyperylenequinone melanin via oxidative aryl coupling by cytochrome P-450 in Streptomyces griseus
N Funa et al.
JOURNAL OF BACTERIOLOGY (2005)
Biocatalytic conversion of avermectin to 4-oxo-avermectin:: Heterologous expression of the ema1 cytochrome P450 monooxygenase
I Molnár et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2005)
Biocatalytic conversion of avermectin to 4-oxo-avermectin:: Characterization of biocatalytically active bacterial strains and of cytochrome P450 monooxygenase enzymes and their genes
V Jungmann et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2005)
In vitro reconstitution of EryCIII activity for the preparation of unnatural macrolides
YQ Yuan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups
M Carmody et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine:: sugar donor substrate flexibility of the StaG glycosyltransferase
AP Salas et al.
MOLECULAR MICROBIOLOGY (2005)
Cytochrome P450 homolog is responsible for C-N bond formation between aglycone and deoxysugar in the staurosporine biosynthesis of Streptomyces sp TP-A0274
H Onaka et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2005)
Structure and chemistry of cytochrome P450
IG Denisov et al.
CHEMICAL REVIEWS (2005)
AknT is an activating protein glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A
W Lu et al.
CHEMISTRY & BIOLOGY (2005)
Binding of two flaviolin substrate molecules, oxidative coupling, and crystal structure of Streptomyces coelicolor A3(2) cytochrome P450 158A2
B Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases
W Liu et al.
CHEMISTRY & BIOLOGY (2005)
Characterization of the polyene macrolide P450 epoxidase from Streptomyces natalensis that converts de-epoxypimaricin into pimaricin
MV Mendes et al.
BIOCHEMICAL JOURNAL (2005)
Availability of specific reductases controls the temporal activity of the cytochrome P450 complement of Streptomyces coelicolor A3(2)
L Lei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Formation of the aureothin tetrahydrofuran ring by a bifunctional cytochrome P450 monooxygenase
J He et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Conversion of vitamin D3 to 1α,25-dihydroxyvitamin D3 by Streptomyces griseolus cytochrome P450SU-1
N Sawada et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Bacterial P450-catalyzed polyketide hydroxylation on a microfluidic platform
A Srinivasan et al.
BIOTECHNOLOGY AND BIOENGINEERING (2004)
Characterization of the glycosyltransferase activity of DesVII:: Analysis of and implications for the biosynthesis of macrolide antibiotics
SA Borisova et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Comparison of the 1.85 A structure of CYP154A1 from Streptomyces coelicolor A3(2) with the closely related CYP154C1 and CYPs from antibiotic biosynthetic pathways
LM Podust et al.
PROTEIN SCIENCE (2004)
An oxidative phenol coupling reaction catalyzed by OxyB, a cytochrome p450 from the vancomycin-producing microorganism
K Zerbe et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tu4055:: insights into nitrile formation
C Olano et al.
MOLECULAR MICROBIOLOGY (2004)
Genome analyses of Streptomyces peucetius ATCC 27952 for the identification and comparison of cytochrome P450 complement with other Streptomyces
N Parajuli et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
Biosynthesis of deoxyamphotericins and deoxyamphoteronolides by engineered strains of Streptomyces nodosus
B Byrne et al.
CHEMISTRY & BIOLOGY (2003)
Export of a heterologous cytochrome P450 (CYP105D1) in Escherichia coli is associated with periplasmic accumulation of uroporphyrin
MK Akhtar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226
YH Sun et al.
ARCHIVES OF MICROBIOLOGY (2003)
Cytochrome P450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2)
DC Lamb et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Ferredoxin reductase enhances heterologously expressed cytochrome CYP105D1 in Escherichia coli and Streptomyces lividans
HA Hussain et al.
ENZYME AND MICROBIAL TECHNOLOGY (2003)
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism
S Mochizuki et al.
MOLECULAR MICROBIOLOGY (2003)
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis
H Ikeda et al.
NATURE BIOTECHNOLOGY (2003)
The 1.92-Å structure of Streptomyces coelicolor A3(2) CYP154C1 -: A new monooxygenase that functionalizes macrolide ring systems
LM Podust et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450
D Leys et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Characterization of the biosynthetic gene cluster of rebeccamycin from Lechevalieria aerocolonigenes ATCC 39243
H Onaka et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2003)
Enhanced heterologous expression of two Streptomyces griseolus cytochrome P450s and Streptomyces coelicolor ferredoxin reductase as potentially efficient hydroxylation catalysts
HA Hussain et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2003)
Reactions catalyzed by bacterial cytochromes P450
MJ Cryle et al.
AUSTRALIAN JOURNAL OF CHEMISTRY (2003)
Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics
F Pojer et al.
MICROBIOLOGY-SGM (2002)
Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp TP-A0274 and its heterologous expression in Streptomyces lividans
H Onaka et al.
JOURNAL OF ANTIBIOTICS (2002)
Cloning and function of sanQ:: A gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes
HM Zeng et al.
CURRENT MICROBIOLOGY (2002)
One fold with many functions: The evolutionary relationships between TIM barrel families based on their sequences, structures and functions
N Nagano et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus TO 6040
U Galm et al.
ARCHIVES OF MICROBIOLOGY (2002)
Oxidizing species in the mechanism of cytochrome P450
PRO de Montellano et al.
NATURAL PRODUCT REPORTS (2002)
The cytochrome p450 complement (CYPome) of Streptomyces coelicolor A3(2)
DC Lamb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Identification of a new class of cytochrome P450 from a Rhodococcus sp.
GA Roberts et al.
JOURNAL OF BACTERIOLOGY (2002)
Sterol 14α-demethylase activity in Streptomyces coelicolor A3(2) is associated with an unusual member of the CYP51 gene family
DC Lamb et al.
BIOCHEMICAL JOURNAL (2002)
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)
SD Bentley et al.
NATURE (2002)
P450BM3: the very model of a modern flavocytochrome
AW Munro et al.
TRENDS IN BIOCHEMICAL SCIENCES (2002)
Parallel pathways for oxidation of 14-membered polyketide macrolactones in Saccharopolyspora erythraea
S Gaisser et al.
MOLECULAR MICROBIOLOGY (2002)
Involvement of a cytochrome P450 monooxygenase in thaxtomin a biosynthesis by Streptomyces acidiscabies
FG Healy et al.
JOURNAL OF BACTERIOLOGY (2002)
Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae
YJ Yoon et al.
CHEMISTRY & BIOLOGY (2002)
Formation of beta-hydroxy histidine in the biosynthesis of nikkomycin antibiotics
H Chen et al.
CHEMISTRY & BIOLOGY (2002)
The candicidin gene cluster from Streptomyces griseus IMRU 3570
AB Campelo et al.
MICROBIOLOGY-SGM (2002)
Isolation and structure determination of novamethymycin, a new bioactive metabolite of the methymycin biosynthetic pathway in Streptomyces venezuelae
QB Zhang et al.
JOURNAL OF NATURAL PRODUCTS (2001)
Genome sequence of an industrial microorganism Streptomyces avermitilis:: Deducing the ability of producing secondary metabolites
S Omura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Bioconversion of the anthracycline analogue desacetyladriamycin by recombinant DoxA, a p450-monooxygenase from Streptomyces sp strain c5
RJ Walczak et al.
ORGANIC LETTERS (2001)
Engineered biosynthesis of novel polyenes:: a pimaricin derivative produced by targeted gene disruption in Streptomyces natalensis
MV Mendes et al.
CHEMISTRY & BIOLOGY (2001)
Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity
FP Guengerich
CHEMICAL RESEARCH IN TOXICOLOGY (2001)
Export of cytochrome P450 105D1 to the periplasmic space of Escherichia coli
MA Kaderbhai et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2001)
Coumarin formation in novobiocin biosynthesis:: β-hydroxylation of the aminoacyl enzyme tyrosyl-S-NovH by a cytochrome P450 NovI
HW Chen et al.
CHEMISTRY & BIOLOGY (2001)
Deletion of rapQNML from the rapamycin gene cluster of Streptomyces hygroscopicus gives production of the 16-O-desmethyl-27-desmethoxy analog
L Chung et al.
JOURNAL OF ANTIBIOTICS (2001)
Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus':: evidence for the derailment of an aromatic polyketide synthase
J Piel et al.
CHEMISTRY & BIOLOGY (2000)
Identification of the coumermycin A1 biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489
ZX Wang et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2000)
Engineering of heterologous cytochrome P450 in Acinetobacter sp.:: Application for pollutant degradation
DC Lamb et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455:: analysis of the gene cluster and deduction of the biosynthetic pathway
T Brautaset et al.
CHEMISTRY & BIOLOGY (2000)
Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin
S Shah et al.
JOURNAL OF ANTIBIOTICS (2000)
The catalytic pathway of cytochrome P450cam at atomic resolution
I Schlichting et al.
SCIENCE (2000)
Molecular characterization of two genes from Streptomyces tendae Tu901 required for the formation of the 4-formyl-4-imidazolin-2-one-containing nucleoside moiety of the peptidyl nucleoside antibiotic nikkomycin
B Lauer et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
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