4.8 Article

Tunable fabrication of folic acid-Au@poly(acrylic acid)/mesoporous calcium phosphate Janus nanoparticles for CT imaging and active-targeted chemotherapy of cancer cells

Journal

NANOSCALE
Volume 9, Issue 38, Pages 14322-14326

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7nr05382g

Keywords

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Funding

  1. National Natural Science Foundation of China [21573040, 21401013, 21301027]
  2. Natural Science Foundation of Jilin Province [20140520088JH, 20150204086GX]
  3. Fundamental Research Funds for the Central Universities [2412016KJ007, 2412016KJ020]
  4. Jilin Provincial Research Foundation for Basic Research [20160519012JH]
  5. Science and Technology Development Planning of Jilin Province [20140520088JH, 20150204086GX]

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A novel, facile and reproducible method was explored to construct uniform folic acid-Au@ poly(acrylicacid)/mesoporous calcium phosphate Janus nanoparticles (FA-Au@PAA/mCaP JNPs), which act as an efficient nanoplatform for X-ray computed tomography (CT) imaging and active-targeted chemotherapy in vitro.

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