Journal
MOLECULES
Volume 22, Issue 9, Pages -Publisher
MDPI
DOI: 10.3390/molecules22091445
Keywords
gold nanoparticles; drug delivery; molecular nanoprobes; imaging; disease diagnosis
Funding
- National Natural Science Foundation of China [21575123, 21675139, 21603184]
- opening project of Jiangsu Key Laboratory of Biochemistry and Biotechnology of Marine Wetland [K2016-17, K2016-20]
- Qing Lan Project
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Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Advances in nanotechnology have led to new and improved nanomaterials in biomedical applications. Common nanomaterials applicable in biomedical applications include liposomes, polymeric micelles, graphene, carbon nanotubes, quantum dots, ferroferric oxide nanoparticles, gold nanoparticles (Au NPs), and so on. Among them, Au NPs have been considered as the most interesting nanomaterial because of its unique optical, electronic, sensing and biochemical properties. Au NPs have been potentially applied for medical imaging, drug delivery, and tumor therapy in the early detection, diagnosis, and treatment of diseases. This review focuses on some recent advances in the use of Au NPs as drug carriers for the intracellular delivery of therapeutics and as molecular nanoprobes for the detection and monitoring of target molecules.
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