Journal
MOLECULES
Volume 22, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/molecules22060966
Keywords
fluorine; trifluoromethoxy; amides
Funding
- CNRS
- University of Versailles
- French Ministry of Research
- French Fluorine Network
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We describe the first gram scale preparation of the reagent dichlorotrifluoromethoxyacetic acid. This stable compound is obtained in five steps starting from the cheap diethylene glycol. The reactivity of the sodium salt of this fluorinated acid was also tested and allowed the preparation of new amides.
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