Journal
MOLECULES
Volume 22, Issue 5, Pages -Publisher
MDPI
DOI: 10.3390/molecules22050828
Keywords
Nicandra physaloides; phenyl-glycosides; fat glycosides; RAW 264.7; inflammation
Funding
- Changjiang Scholars Back-Up Program of Heilongjiang Universities Colleges [2013CJHB006]
- Chinese Medicine of Heilongjiang [ZHY16-091]
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Three new glycosides (1-3) and 15 known ones (4-18) were isolated and identified from the fruits of Nicandra physaloides. The structures of these compounds were established by 1D and 2D NMR spectra and HR- ESI- MS. The compounds (4- 18) were the first time isolated from the Nicandra genus and they (except 8, 10, 14) exhibited inhibitions on the NO release of LPS- induced RAW 264.7 cells with IC50 values from 26.9 to 47.5 mu M.
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