Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 17, Issue 1, Pages 35-38Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob02660b
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- AMOLF
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A simple route to enantiomerically pure (S)-2-aminobutyramide - the chiral component of the anti-epileptic drugs Levetiracetam and Brivaracetam has been developed. This approach is based on the rational design and application of a Viedma ripening process. The practical potential of the process is demonstrated on a large scale.
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