Journal
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
Volume 12, Issue -, Pages 13-23Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/IJGM.S186854
Keywords
cholangiocarcinoma; etiology; diagnosis; treatment; bile ducts
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Funding
- Welcome Trust ISSF Fund at Imperial College, London
- AMMF - the Cholangiocarcinoma Charity (Stansted, Essex, UK)
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Cholangiocarcinoma (CCA) is a tumor with increasing prevalence around the world. The prevalence of CCA is highest in East Asia and most significantly in the countries through which the Mekong River flows, owing to the presence of liver flukes, which are consumed in raw fish dishes. Outside Asia, the causes of bile duct cancers for the most part are unknown. In this review, we assess the current state of knowledge in both fluke-associated and sporadic CCA, from etiological, diagnostic, and treatment perspectives.
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