Journal
BMC RESEARCH NOTES
Volume 12, Issue -, Pages -Publisher
SPRINGERNATURE
DOI: 10.1186/s13104-019-4067-9
Keywords
EQ-5D-5L utility index; Clinical studies; Country differences; Quality of life valuation
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ObjectiveTo compare the country-specific value sets of the EQ-5D-5L utility index and to evaluate the impact on the interpretation of clinical study results. Six country value sets from Canada, England, Japan, Korea, Netherlands and Uruguay were obtained from literature. In addition, ten crosswalk value sets were downloaded from the EuroQol.org website.ResultsFor each of the 3125 possible health states the difference between the country with the highest index and the country with the lowest index was calculated. The median difference was 0.417 across the health states. When analyzing multinational clinical studies, country-specific value sets should be used to evaluate treatment effects. Additional country-specific analyses are needed.
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