4.6 Review

Hutchinson-Gilford Progeria Syndrome: A Premature Aging Disease

Related references

Note: Only part of the references are listed.
Article Cardiac & Cardiovascular Systems

Impact of Farnesylation Inhibitors on Survival in Hutchinson-Gilford Progeria Syndrome

Leslie B. Gordon et al.

CIRCULATION (2014)

Article Clinical Neurology

Imaging Characteristics of Cerebrovascular Arteriopathy and Stroke in Hutchinson-Gilford Progeria Syndrome

V. M. Silvera et al.

AMERICAN JOURNAL OF NEURORADIOLOGY (2013)

Article Multidisciplinary Sciences

Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome

Leslie B. Gordon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biochemistry & Molecular Biology

Structure and stability of the lamin A tail domain and HGPS mutant

Zhao Qin et al.

JOURNAL OF STRUCTURAL BIOLOGY (2011)

Article Cell Biology

Premature aging-related peripheral neuropathy in a mouse model of progeria

James R. Goss et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2011)

Article Cell Biology

The nuclear envelope at a glance

Katherine L. Wilson et al.

JOURNAL OF CELL SCIENCE (2010)

Article Cell Biology

Diseases of the Nuclear Envelope

Howard J. Worman et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)

Article Cell Biology

Telomere length in Hutchinson-Gilford Progeria Syndrome

Michelle L. Decker et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2009)

Editorial Material Medicine, General & Internal

Focus on research: Hutchinson-Gilford progeria syndrome, aging, and the nuclear lamina

Bruce Korf

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Article Medicine, General & Internal

Phenotype and course of Hutchinson-Gilford progeria syndrome

Melissa A. Merideth et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Review Biochemistry & Molecular Biology

From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing

L. S. Cox et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2007)

Review Oncology

Laminopathies: A wide spectrum of human diseases

Howard J. Worman et al.

EXPERIMENTAL CELL RESEARCH (2007)

Review Cell Biology

Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases

Brian A. Kudlow et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)

Article Multidisciplinary Sciences

A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells

Kan Cao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Clinical Neurology

Mechanisms of Disease: DNA repair defects and neurological disease

Kalluri Subba Rao

NATURE CLINICAL PRACTICE NEUROLOGY (2007)

Article Multidisciplinary Sciences

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis

Laura J. Niedernhofer et al.

NATURE (2006)

Review Genetics & Heredity

Hutchinson-Gifford Progeria syndrome: Review of the phenotype

Raoul C. M. Hennekam

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2006)

Article Biochemistry & Molecular Biology

Lamins A and C but not lamin B1 regulate nuclear mechanics

Jan Lammerding et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Compound heterozygosity for mutations in LMNA causes a Progeria syndrome without prelamin A accumulation

Valerie L. R. M. Verstraeten et al.

HUMAN MOLECULAR GENETICS (2006)

Article Cell Biology

Expression of disease-causing lamin A mutants impairs the formation of DNA repair foci

Kaliyaperumal Manju et al.

JOURNAL OF CELL SCIENCE (2006)

Review Physiology

Nuclear lamins: Laminopathies and their role in premature ageing

J. L. V. Broers et al.

PHYSIOLOGICAL REVIEWS (2006)

Article Multidisciplinary Sciences

Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

Dale K. Shumaker et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

Lamin A-dependent nuclear defects in human aging

P Scaffidi et al.

SCIENCE (2006)

Article Medicine, Research & Experimental

Prelamin A and lamin A appear to be dispensable in the nuclear lamina

LG Fong et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Cell Biology

Here come the SUNs: a nucleocytoskeletal missing link

HJ Worman et al.

TRENDS IN CELL BIOLOGY (2006)

Article Multidisciplinary Sciences

Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes

JI Toth et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Genomic instability in laminopathy-based premature aging

BH Liu et al.

NATURE MEDICINE (2005)

Review Cell Biology

A-type nuclear lamins, progerias and other degenerative disorders

ED Smith et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2005)

Article Biochemistry & Molecular Biology

Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome

P Scaffidi et al.

NATURE MEDICINE (2005)

Review Biochemistry & Molecular Biology

Understanding the odd science of aging

TBL Kirkwood

Review Biochemistry & Molecular Biology

DNA repair, genome stability, and aging

DB Lombard et al.

Article Genetics & Heredity

LMNA mutation in a 45 year old Japanese subject with Hutchinson-Gilford progeria syndrome

K Fukuchi et al.

JOURNAL OF MEDICAL GENETICS (2004)

Article Genetics & Heredity

Novel lamin A/C gene (LMNA) mutations in atypical progeroid syndromes

AB Csoka et al.

JOURNAL OF MEDICAL GENETICS (2004)

Article Medicine, Research & Experimental

Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C-deficient mice

V Nikolova et al.

JOURNAL OF CLINICAL INVESTIGATION (2004)

Article Endocrinology & Metabolism

The GH/IGF-I axis and longevity

M Holzenberger

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2004)

Article Multidisciplinary Sciences

Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice

LG Fong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Multidisciplinary Sciences

Lamin B1 is required for mouse development and nuclear integrity

L Vergnes et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Multidisciplinary Sciences

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome

RD Goldman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Medicine, General & Internal

LMNA mutations in atypical Werner's syndrome

LS Chen et al.

LANCET (2003)

Article Multidisciplinary Sciences

Lamin A truncation in Hutchinson-Gilford progeria

A De Sandre-Giovannoli et al.

SCIENCE (2003)

Article Genetics & Heredity

Del(1)(q23) in a patient with Hutchinson-Gilford progeria

WD Luengo et al.

AMERICAN JOURNAL OF MEDICAL GENETICS (2002)

Article Cardiac & Cardiovascular Systems

Fatal pulmonary hypertension associated with an atypical case of Hunchinson-Gilford progeria

I Shiraishi et al.

PEDIATRIC CARDIOLOGY (2001)

Review Medicine, General & Internal

Hutchinson-Guilford progeria syndrome

PK Sarkar et al.

POSTGRADUATE MEDICAL JOURNAL (2001)