Journal
MOLECULAR CELL
Volume 66, Issue 4, Pages 439-441Publisher
CELL PRESS
DOI: 10.1016/j.molcel.2017.05.005
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Although H3K4me1 is a pervasive mark'' of enhancers, its functional requirement for enhancer activity remains unclear. In this issue of Molecular Cell, Dorighi et al. (2017) show that in some contexts, the methyltransferase complex, rather than the H3K4me1 mark, is required for gene expression.
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