Journal
MOLECULAR CELL
Volume 65, Issue 6, Pages 961-962Publisher
CELL PRESS
DOI: 10.1016/j.molcel.2017.02.029
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Dong et al. (2017) establish how the mitochondrial Ca2+ uniporter (MCU) integrates Ca2+ and oxidative stress signals by identifying a cysteine residue that controls MCU channel activity, a mechanism causing mitochondrial Ca2+ overload and cell death during oxidative stress.
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