4.8 Editorial Material

Expanding the CRISPR Toolbox: Targeting RNA with Cas13b

Journal

MOLECULAR CELL
Volume 65, Issue 4, Pages 582-584

Publisher

CELL PRESS
DOI: 10.1016/j.molcel.2017.02.002

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Funding

  1. Div Of Chem, Bioeng, Env, & Transp Sys
  2. Directorate For Engineering [1151035] Funding Source: National Science Foundation

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In this issue of Molecular Cell, Smargon et al. (2017) unearth Cas13b from type VI-B CRISPR-Cas immune systems and characterize its RNA-guided, RNA-targeting activity, including regulation by the novel co-factors Csx27 and Csx28, as well as non-specific collateral RNA damage.

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