Journal
MITOCHONDRION
Volume 34, Issue -, Pages 127-134Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.mito.2017.03.004
Keywords
Cardiac; Ischemia; Mitochondria; Reperfusion
Categories
Funding
- Richard and Susan Smith Foundation
- Sidman Family Foundation
- Bulens/Capozzi Foundation
- Boston Children's Hospital Anesthesia Foundation
- Kenneth C. Griffin Charitable Research Fund
- Boston Investment Council
- Boston Children's Hospital
- President's Innovation Award
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Mitochondrial transplantation is a novel therapeutic intervention to treat ischemia/reperfusion related disorders. The method for mitochondrial transplantation is simple and rapid and can be delivered to the end organ either by direct injection or vascular infusion. In this review, we provide mechanistic and histological studies in large animal models and present data to show clinical efficacy in human patients. (C) 2017 Published by Elsevier B.V.
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