Journal
DALTON TRANSACTIONS
Volume 48, Issue 5, Pages 1569-1573Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8dt03948h
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Funding
- Natural Science Foundation of China [21877049, 21701051]
- National Program for Support of Top-notch Young Professionals [W02070191]
- Natural Science Foundation of Guangdong Province [2017A030313051]
- China Postdoctoral Science Foundation [2016M600705]
- Fundamental Research Funds for the Central Universities
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Herein we designed and synthesized a cell penetrating peptide- and cancer-targeted molecule-functionalized multi-walled carbon nanotube for precise orthotopic glioma therapy. In addition to reduced toxicity, this nanosystem exhibited enhanced cancer recognition, blood-brain barrier (BBB) penetration, and anticancer activity through increased ROS production.
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