Journal
MICROFLUIDICS AND NANOFLUIDICS
Volume 21, Issue 12, Pages -Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s10404-017-2015-3
Keywords
-
Funding
- Spanish government
- AEI/FEDER, UE [MAT2016-75716-C2-1-R]
- Ministerio de Economia y Competitividad [MAT2013-47395- C4-4-R, TEC2014-55948-R, CTQ2014-59808R]
- Generalitat de Catalunya [2014SGR1358, 2014SGR480]
- HM Group Hospitales
- European Union [712.949]
- Agencia para la Competitividad de la Empresa de la Generalidad de Cataluna
Ask authors/readers for more resources
This paper presents an optofluidic device for cell discrimination with two independent interrogation regions. Pumping light is coupled to the device, and cell fluorescence is extracted from the two interrogation zones by using optical fibers embedded in the optofluidic chip. To test the reliability of this device, AU-565 cells-expressing EpCAM and HER2 receptors-and RAMOS cells were mixed in a controlled manner, confined inside a hydrodynamic focused flow in the microfluidic chip and detected individually so that they could be discriminated as positive (signal reception from fluorescently labeled antibodies from the AU-565 cells) or negative events (RAMOS cells). A correlation analysis of the two signals reduces the influence of noise on the overall data.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available