Journal
BMC CHEMISTRY
Volume 13, Issue -, Pages -Publisher
BMC
DOI: 10.1186/s13065-019-0536-4
Keywords
Annona squamosa; Annonacea; (6,7-dimethoxy-1-(alpha-hydroxy-4-methoxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin; Coclaurine
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Funding
- Deanship of Scientific Research at King Khalid University [G. R.P- 281-38]
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Two alkaloids, belonging to benzylisoquinoline alkaloids, were isolated from Annona squamosa. One of these alkaloids, 6, 7-dimethoxy-1-(alpha-hydroxy-4-methoxybenzyl)-2-methyl-1, 2, 3, 4-tetrahydroisoquinoline, was isolated for the first time from natural sources, while, the alkaloid, Coclaurine was known in Annona squamosa L. Moreover, the isolated alkaloids tested for the anti-cancer activities on various cell lines (HepG-2, MCF-7, and HCT-116).
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