4.7 Article

A stimuli-responsive DNAzyme displaying Boolean logic-gate responses

Journal

CHEMICAL COMMUNICATIONS
Volume 55, Issue 13, Pages 1959-1962

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc09345h

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Funding

  1. Japan Society for the Promotion of Science [15H03836]
  2. Daiichi Sankyo Foundation of Life Science
  3. Grants-in-Aid for Scientific Research [15H03836] Funding Source: KAKEN

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Introducing a desired stimuli-responsive function into catalytically active biomacromolecules is potentially useful in developing molecular tools for various bio-applications. In this paper, we discuss the development of a stimuli-responsive DNAzyme (catalytic deoxyribozyme) capable of displaying Boolean logic-gate responses.

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