Journal
MICROCHIMICA ACTA
Volume 184, Issue 5, Pages 1267-1283Publisher
SPRINGER WIEN
DOI: 10.1007/s00604-017-2179-2
Keywords
Cellular signalling; Cellular stress; Amperometry; Carbon nanomaterial; Noble metal nanoparticles; Metal oxide nanoparticles; Layered double hydroxide; Reactive oxygen species; Reactive nitrogen species; Reactive hydrogen sulfide species
Categories
Funding
- National Natural Science Foundation of China [61404075, 21405029]
- China Postdoctoral Science Foundation [2016 M601694]
- Jiangsu Planned Projects for Postdoctoral Research Funds [1601090B]
- Science and Technology Program of Zhejiang Province of China [2016C37042]
- Young Talent Cultivation Project of Zhejiang Association for Science and Technology [2016YCGC007]
- social development project of Hangzhou [20160533B70]
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The incorporation of nanomaterials into electrochemical sensors is an attractive approach towards the improvement of the sensitivity of amperometry and also can provide improved sensor selectivity and stability. This review (with 137 references) details the current state of the art and new trends in nanomaterial-based electrochemical sensing of hydrogen peroxide (H2O2), hydrogen sulfide (H2S) and nitric oxide (NO) in cells or released by cells. The article starts with a discussion of the significance of the three analytes, and this is followed by three sections that summarize the electrochemical detection schemes for H2O2, H2S and NO. Each section first summarizes the respective physiological roles, and then reviews electrochemical sensors based on the use of carbon nanomaterials, noble metal nanomaterials, metal oxide nanomaterials, and layered doubled hydroxides. The materials are compiled in three tables along with figures of merit for the various sensors.
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