4.5 Article

Screening for Oral Cancer Using Electrochemical Telomerase Assay

Journal

ELECTROANALYSIS
Volume 28, Issue 3, Pages 503-507

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/elan.201500426

Keywords

telomerase; hTERT gene; oral cancer screening; electrochemical assay

Funding

  1. JSPS KAKENHI [25861969, 26463074]
  2. Grants-in-Aid for Scientific Research [26463074, 25861969] Funding Source: KAKEN

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Electrochemical telomerase assay (ECTA) developed by our group was evaluated in an oral cancer screening using exfoliated oral cells and tissues obtained from patients of oral cancer, mucosa associated disease, or healthy volunteers. Telomerase activity from ECTA is correlated with hTERT mRNA expression level using a real-time PCR and was increasing in the following order: healthy volunteer group

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