4.7 Article

Glucose oxidase assisted visual detection of glucose using oxygen deficient alpha-MoO3-x nanoflakes

Journal

MICROCHIMICA ACTA
Volume 185, Issue 1, Pages -

Publisher

SPRINGER WIEN
DOI: 10.1007/s00604-017-2612-6

Keywords

Two dimensional nanoflakes; Transition metal oxides; Molybdenum trioxide; Hydrogen peroxide; Visual test; Rapid detection; Colorimetry

Funding

  1. Ministry of Science and Technology (MOST), Taiwan [MOST 104-2113-M-110-003-MY3]

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An optical method is described for the quantitation of glucose by using oxygen-deficient alpha-MoO3-x nanoflakes. It is based on the use of glucose oxidase (GOx) which produces hydrogen peroxide on oxidation of glucose. Hydrogen peroxide then oxidizes the alpha-MoO3-x nanoflakes, and this results in a visible color change from blue to colorless. The color change can be measured photometrically at 740 nm. The method has a 68 nM detection limit.

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