Journal
CHEMICAL COMMUNICATIONS
Volume 55, Issue 17, Pages 2477-2480Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc10084e
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Funding
- NSFC [21462007, 21002015, 21662004]
- State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources [EMEMR 2015-A03, 2018-C20]
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A series of near-infrared fluorescent probes based on inhibitor (clorgyline) structure-guided design were synthesized for the specific detection of MAO-A in cells and in vivo. Moreover, we have successfully used the high specificity of one of the probes to visualize MAO-A activity in zebrafish and tumor tissue for the first time.
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