Journal
BIOELECTRICITY
Volume 1, Issue 1, Pages 30-+Publisher
MARY ANN LIEBERT, INC
DOI: 10.1089/bioe.2018.0001
Keywords
electroporation; pulsed electric fields; electrochemotherapy; gene electrotransfer; irreversible electroporation; Nano-Pulse Stimulation
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This review covers the use of pulsed electric fields in cancer therapy. It is organized into three sections based on pulse length, millisecond domain, microsecond domain, and nanosecond domain. The predominant application of pulsed electric fields is the modification of the permeability of cellular membranes, sometimes referred to as electroporation. This has been used in many different ways for cancer treatment. These include introducing genes into the tumor cells to activate an immune response, introducing poisons into the tumor cells, initiating necrosis using irreversible electroporation, and initiating immunogenic cell death with nanopulse stimulation.
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