Journal
METABOLIC ENGINEERING
Volume 42, Issue -, Pages 98-108Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ymben.2017.06.003
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Funding
- Roy J. Carver Charitable Trust [13-4257]
- Carl R. Woese Institute for Genomic Biology at the University of Illinois at Urbana-Champaign (UIUC)
- Defense Advanced Research Program Agency
- National Institutes of Health [1U54DK107965]
- 3M Corporation
- Carl R. Woese Institute for Genomic Biology (UIUC)
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Engineered biological systems such as genetic circuits and microbial cell factories have promised to solve many challenges in the modern society. However, the artisanal processes of research and development are slow, expensive, and inconsistent, representing a major obstacle in biotechnology and bioengineering. In recent years, biological foundries or biofoundries have been developed to automate design-build-test engineering cycles in an effort to accelerate these processes. This review summarizes the enabling technologies for such biofoundries as well as their early successes and remaining challenges.
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