Journal
METABOLIC BRAIN DISEASE
Volume 32, Issue 4, Pages 1069-1072Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s11011-017-9989-0
Keywords
MELAS; Aneurysm; Nitric oxide synthase; Apoptosis
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We reported a 53-year-old with late-onset mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) accompanied by aneurysm and large vessel dilations. Most studies have focused on microangiopathy causing stroke-like episodes. We report a case to describe large vessel involvement in clinical considerations, and possible mechanisms of aneurysm formation. We recommended regular angiographic examination for patients with MELAS.
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