Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 17, Issue 8, Pages 2199-2203Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob03057j
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Funding
- National Natural Science Foundation of China (NSFC) [21506191, 21676252]
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A straightforward method for the synthesis of indolin-3-ones bearing a C2-quaternary functionality is reported. A series of 2,2-disubstituted indolin-3-ones were constructed in up to 94% yields in the absence of a metal catalyst. This cross-coupling reaction allows the facile synthesis of 2,2-disubstituted indolin-3-ones from readily available substrates in a short reaction time.
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