Journal
MEMORIAS DO INSTITUTO OSWALDO CRUZ
Volume 113, Issue 2, Pages 135-136Publisher
FUNDACO OSWALDO CRUZ
DOI: 10.1590/0074-02760170347
Keywords
yellow fever vaccine; single dose vaccine; multiple dose vaccine; WHO; life-long immunity
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The yellow fever (YF) vaccine has been used since the 1930s to prevent YF, which is a severe infectious disease caused by the yellow fever virus (YFV), and mainly transmitted by Culicidae mosquitoes from the genera Aedes and Haemagogus. Until 2013, the World Health Organization (WHO) recommended the administration of a vaccine dose every ten years. A new recommendation of a single vaccine dose to confer life-long protection against YFV infection has since been established. Recent evidence published elsewhere suggests that at least a second dose is needed to fully protect against YF disease. Here, we discuss the feasibility of administering multiple doses, the necessity for a new and modern vaccine, and recommend that the WHO conveys a meeting to discuss YFV vaccination strategies for people living in or travelling to endemic areas.
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