Journal
CHEMICAL COMMUNICATIONS
Volume 55, Issue 16, Pages 2340-2343Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc09432b
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Funding
- Science and Technology Development Fund, Macao SAR [FDCT 030/2017/A1]
- Research Committee at University of Macau [MYRG2016-00165-ICMS-QRCM, MYRG2017-00010-ICMS]
- National Natural Science Foundation of China [21525206, 21472202, 21871301]
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Paclitaxel-loaded nanoparticles based on a bispillar[5]arene compound were successfully developed using a microemulsion method for the first time. The nanoparticles exhibited dual stimuli-responsiveness towards both spermine and glutathione, allowing precisely selective drug release in lung cancer cells that overexpress both stimuli.
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