4.7 Article

Deep learning-based super-resolution in coherent imaging systems

Journal

SCIENTIFIC REPORTS
Volume 9, Issue -, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41598-019-40554-1

Keywords

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Funding

  1. NSF Engineering Research Center (ERC, PATHS-UP)
  2. Army Research Office (ARO) [W911NF-13-1-0419, W911NF-13-1-0197]
  3. ARO Life Sciences Division
  4. National Science Foundation (NSF) CBET Division Biophotonics Program
  5. NSF Emerging Frontiers in Research and Innovation (EFRI) Award
  6. NSF INSPIRE Award
  7. NSF Partnerships for Innovation: Building Innovation Capacity (PFI:BIC) Program
  8. National Institutes of Health (NIH) [R21EB023115]
  9. Howard Hughes Medical Institute (HHMI)
  10. Vodafone Americas Foundation
  11. Mary Kay Foundation
  12. Steven & Alexandra Cohen Foundation

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We present a deep learning framework based on a generative adversarial network (GAN) to perform super-resolution in coherent imaging systems. We demonstrate that this framework can enhance the resolution of both pixel size-limited and diffraction-limited coherent imaging systems. The capabilities of this approach are experimentally validated by super-resolving complex-valued images acquired using a lensfree on-chip holographic microscope, the resolution of which was pixel size-limited. Using the same GAN-based approach, we also improved the resolution of a lens-based holographic imaging system that was limited in resolution by the numerical aperture of its objective lens. This deep learning-based super-resolution framework can be broadly applied to enhance the space-bandwidth product of coherent imaging systems using image data and convolutional neural networks, and provides a rapid, non-iterative method for solving inverse image reconstruction or enhancement problems in optics.

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