Journal
BIO-DESIGN AND MANUFACTURING
Volume 2, Issue 1, Pages 24-30Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s42242-019-00034-x
Keywords
Biomedical devices; Intradermal; Intracellular; 1D nanostructure; Drug delivery
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Funding
- Tongji University
- National Natural Science Foundation of China [51875518, 81501607, 51475419]
- Key Research and Development Projects of Zhejiang Province [2017C01054]
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The advancement in the materials manufacturing at micrometer and nanometer scales has already enabled numerous applications in electronics, optics, chemistry, biology and medicine. Biomedical devices carrying micro-/nanostructures are currently being widely used in drug delivery, drug release, biosensing and therapy. New clinical methods for disease diagnosis and treatments are being developed enabled by nanotechnology. One-dimensional (1D) structures are playing an important role in the direct drug delivery both in vivo and ex vivo among various micro-/nanostructures. Here, in this paper, we reviewed recent progresses made on next-generation intradermal and intracellular delivery strategies and applications with focus on 1D microstructure-based approaches.
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