4.7 Article

Decarboxylative hydrazination of unactivated carboxylic acids by cerium photocatalysis

Journal

CHEMICAL COMMUNICATIONS
Volume 55, Issue 24, Pages 3489-3492

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc00492k

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Funding

  1. European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme [741623]
  2. Elitenetzwerk Bayern (SynCat)

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We report the cerium photocatalyzed radical decarboxylative hydrazination of carboxylic acids with di-tert-butylazodicarboxylate (DBAD). The operationally simple protocol provides rapid access to synthetically useful hydrazine derivatives and overcomes current scope limitations in the photoredox-catalyzed decarboxylation of carboxylic acids.

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