Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 17, Issue 13, Pages 3333-3337Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9ob00294d
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Funding
- National Natural Science Foundation of China [21307021, 21502175]
- Open Project of the Grain&Corn Engineering Technology Research Center in the State Administration of Grain [24400042]
- Colleges and Universities Key Research Program Foundation of Henan Province [17A150006]
- Science and Technology Foundation of Henan Province [182102210091]
- Fundamental Research Funds for the Henan Provincial Colleges and Universities in the Henan University of Technology [2015QNJH08]
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An effective copper-catalyzed direct C-H/N-H cross-coupling of quinoxalin-2(1H)-ones with diverse unprotected 2-quinoxalinones and 2-quinolinones has been developed. This protocol provides a convenient route, with broad substrate scope, good functional group tolerance, and high atom economy, to various important quinoxalin-2(1H)-one-containing biheteroaryls, which are privileged structures in many biologically active compounds.
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