Journal
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
Volume 80, Issue -, Pages 54-58Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.msec.2017.05.067
Keywords
Gold nanorods; Localisea surface plasmon resonance; Biofilm; Photothermal therapy; Staphylococcus epiderrnidis
Categories
Funding
- Knut and Alice Wallenberg Foundation
Ask authors/readers for more resources
Antimicrobial resistance is an increasing global health concern and the world is facing a major challenge to develop novel ways of replacing antibiotics. Gold nanorods exhibit localised surface plasmon resonance upon optical irradiation. During relaxation, absorbed energy is dissipated as heat, which has been utilized to kill bacteria. In this study, 10 x 45 nm gold nanorods were attached to glass surfaces using silanisation. Then biofilms were cultured on the surfaces and studied using microscopy. On average, 71% of the early biofilm bacteria were eliminated after 5 min of near infrared radiation (LED emission peak at 850 nm) of the gold nanorod coated surfaces, showing the potential of this novel antibiofilm technique. Most notably, the best individual result showed 97% biofilm elimination. This study demonstrates that nanoplasmonic generated heat offers a novel way of eliminating bacterial biofilms. In future applications, this method may be used to eliminate bacterial contamination during implant surgery. (C) 2017 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available