Journal
ACS OMEGA
Volume 4, Issue 3, Pages 4779-4784Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsomega.8b03685
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Nine new dithiocarbamic esters derived from bio-based acrylic acid were synthesized and evaluated for their in vitro antifungal activity against the phytopathogenic fungus Fusarium solani and fungi-like oomycete Phytophthora infestans. Among these nine dithiocarbamic derivatives, compound 6 (tert-butyl 3-(N,N-diethyldithiocarbamoyl)-propanoate) showed interesting antifungal efficacy at low concentration compared to the other tested dithiocarbamates. The structure-antifungal activity relationship of these designed dithiocarbamic esters is discussed.
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