Journal
FOOD & FUNCTION
Volume 10, Issue 3, Pages 1288-1294Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8fo02549e
Keywords
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Funding
- National Key R&D Program of China [2017YFE0102200]
- National Natural Science Foundation of China [81473103, 81872756]
- Key Technology R&D Program of Zhejiang Province [2018C02034]
- Research Fund of University of Macau [MYRG2017-00109-ICMS, MYRG2018-00037-ICMS]
- Zhejiang Provincial Natural Science Foundation of China [LR17H300001]
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Curcumenol was firstly revealed as a pair of hemiacetal-ketone tautomers in solutions by using temperature variation H-1-NMR experiments, 2D NMR, and chemical methods. Quantum chemical calculation allowed the explanation of its spectroscopic behavior. An antioxidative SAR study on its derivatives verified the tautomeric bio-significance. Curcumenol also remarkably enhanced myogenic differentiation and mitochondrial function.
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