Journal
MASS SPECTROMETRY REVIEWS
Volume 39, Issue 3, Pages 229-244Publisher
WILEY
DOI: 10.1002/mas.21540
Keywords
informatics; quantitative mass spectrometry; targeted proteomics
Categories
Funding
- National Institutes of Health [R01 GM103551, R01 GM121696, P41 GM103533, U54 HG008097, R21 CA192983, P30 AG013280]
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Skyline is a freely available, open-source Windows client application for accelerating targeted proteomics experimentation, with an emphasis on the proteomics and mass spectrometry community as users and as contributors. This review covers the informatics encompassed by the Skyline ecosystem, from computationally assisted targeted mass spectrometry method development, to raw acquisition file data processing, and quantitative analysis and results sharing.
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