4.7 Review

Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms

Journal

MARINE DRUGS
Volume 15, Issue 3, Pages -

Publisher

MDPI
DOI: 10.3390/md15030068

Keywords

marine microbe; sponge-derived microbe; natural product; cytotoxic compound

Funding

  1. Zhejiang Natural Science Foundation of China [LY16H300007, LY16H300008]

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A growing body of evidence indicates that marine sponge-derived microbes possess the potential ability to make prolific natural products with therapeutic effects. This review for the first time provides a comprehensive overview of new cytotoxic agents from these marine microbes over the last 62 years from 1955 to 2016, which are assorted into seven types: terpenes, alkaloids, peptides, aromatics, lactones, steroids, and miscellaneous compounds.

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