Journal
MARINE DRUGS
Volume 15, Issue 2, Pages -Publisher
MDPI AG
DOI: 10.3390/md15020044
Keywords
briarane; octocoral; Briareum; Dichotella; Ellisella; Junceella; Pennatula
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Funding
- National Museum of Marine Biology and Aquarium
- National Dong Hwa University
- National Sun Yat-sen University
- National Research Program for Biopharmaceuticals, Ministry of Science and Technology, Taiwan [105-2325-B-291-001, 105-2811-B-291-003, 104-2320-B-291-001-MY3, 104-2325-B-291-001]
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The structures, names, bioactivities, and references of 124 briarane-type natural products, including 66 new metabolites, isolated between 2014 and 2016 are summarized in this review article. All of the briarane diterpenoids mentioned in this review were isolated from octocorals, mainly from Briareum violacea, Dichotella gemmacea, Ellisella dollfusi, Junceella fragilis, Junceella gemmacea, and Pennatula aculeata. Some of these compounds exhibited potential biomedical activities, including anti- inflammatory activity, antibacterial activity, and cytotoxicity towards cancer cells.
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