Journal
MARINE DRUGS
Volume 15, Issue 9, Pages -Publisher
MDPI AG
DOI: 10.3390/md15090267
Keywords
antifouling; biofouling; barnacle; terpenoid; acetogenin; Laurencia; Rhodophyta
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Funding
- JSPS KAKENHI [16H04975]
- JST
- Grants-in-Aid for Scientific Research [16H04975] Funding Source: KAKEN
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Six new compounds, omaezol, intricatriol, hachijojimallenes A and B, debromoaplysinal, and 11,12-dihydro-3-hydroxyretinol have been isolated from four collections of Laurencia sp. These structures were determined by MS and NMR analyses. Their antifouling activities were evaluated together with eight previously known compounds isolated from the same samples. In particular, omaezol and hachijojimallene A showed potent activities (EC50 = 0.15-0.23 mu g/mL) against larvae of the barnacle Amphibalanus amphitrite.
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