Journal
MARINE DRUGS
Volume 15, Issue 7, Pages -Publisher
MDPI
DOI: 10.3390/md15070202
Keywords
sarcophyton glaucum; lobocrasol; ent-sarcophyolide E; sarcophine
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Funding
- Ministry of Science and Technology [MOST104-2113-M-110-006, 105-2113-M-110-002]
- NSYSU-KMU Joint Research Project (NSYSUKMU) [06C0301709]
- Aim for the TOP University Program from Ministry of Education of Taiwan [05C030205]
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Five new isoprenoids, 3,4,8,16-tetra-epi-lobocrasol (1), 1,15 beta-epoxy-deoxysarcophine (2), 3,4-dihydro-4 alpha,7 beta,8 alpha-trihydroxy-Delta(2)-sarcophine (3), ent-sarcophyolide E (4), and 16-deacetyl-halicrasterol B (5) and ten known compounds 6-15, were characterized from the marine soft coral Sarcophyton glaucum, collected off Taitung coastline. Their structures were defined by analyzing spectra data, especially 2D NMR and electronic circular dichroism (ECD). The structure of the known compound lobocrasol (7) was revised. Cytotoxicity potential of the isolated compounds was reported, too.
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