Journal
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
Volume 31, Issue 1, Pages 19-31Publisher
SPRINGER
DOI: 10.1007/s10334-017-0624-1
Keywords
3-D CINE imaging; Compressed sensing; Ventricular function
Funding
- Erlangen Graduate School in Advanced Optical Technologies (SAOT) by the German Research Foundation (DFG)
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Our objectives were to evaluate a single-breath-hold approach for Cartesian 3-D CINE imaging of the left ventricle with a nearly isotropic resolution of and a breath-hold duration of 19 s against a standard stack of 2-D CINE slices acquired in multiple breath-holds. Validation is performed with data sets from ten healthy volunteers. A Cartesian sampling pattern based on the spiral phyllotaxis and a compressed sensing reconstruction method are proposed to allow 3-D CINE imaging with high acceleration factors. The fully integrated reconstruction uses multiple graphics processing units to speed up the reconstruction. The 2-D CINE and 3-D CINE are compared based on ventricular function parameters, contrast-to-noise ratio and edge sharpness measurements. Visual comparisons of corresponding short-axis slices of 2-D and 3-D CINE show an excellent match, while 3-D CINE also allows reformatting to other orientations. Ventricular function parameters do not significantly differ from values based on 2-D CINE imaging. Reconstruction times are below 4 min. We demonstrate single-breath-hold 3-D CINE imaging in volunteers and three example patient cases, which features fast reconstruction and allows reformatting to arbitrary orientations.
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